This article give a great overview of some of distruption and innovation in the healthcare system. We are in the midst of a (medical) revolution driven by exponential technology: artificial intelligence, sensors, robotics, 3D printing, big data, genomics and stem cells. • AI-enabled autonomous health scans provide the best diagnostics equally to the poorest and wealthiest on Earth. • Large-scale genomic sequencing and machine learning allow us to understand the root cause of cancer, heart disease and neurodegenerative disease and what to do about it. • Wearables, connected devices and quantified-self apps will allow us to collect enormous amounts of useful health information. • Robotic surgeons can carry out a perfect operation (every time) for pennies on the dollar. • When each of us can regrow a heart, liver, lung or kidney when we need it instead of waiting for the donor to die. • On-demand manufacturing will make medical devices cheaper and more readily accessible to millions, and it will make scarce resources like organs-for-transplant abundantly available. • Unlocking secrets of our biology- insights into cancer, heart disease, neurodegenerative disease etc since the cost of genome sequencing has plummeted 100,000-fold, from $100M per genome in 2001 to $1,000 per genome today… outpacing Moore’s Law by 3x. • We are now in the earliest stages of stem cell therapy development. Future therapies will be transformative and, frankly, mind-boggling.